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It is possible to reach 450 Inscription skill, but that will require large amounts of materials after skill 430. Since there is no reason to reach skill 450 yet, consider stopping power-leveling Inscription at about 430.

Materials 350-450

To reach skill 430, you should mill 360 herbs (72 millings) that produce Azure Pigment/Icy Pigment. Any Northrend herb from: Adder's Tongue, Deadnettle, Fire Leaf, Goldclover, Icethorn, Lichbloom, Talandra's Rose, or Tiger Lily. You should gain at least 188 Azure Pigment and about 28 Icy Pigment (the precise number of Icy Pigment is not important).

Recipes in this skill block use Resilient Parchment. You will need about 150 parchment to reach skill 430.

I do not recommend attempting to power-level straight to 450. Those attempting to level quickly from 430 to 450 will need to use extra materials. Full details are described below.

Where can you pick Northrend flowers? The best place to gather large amounts of Northrend herbs is Sholazar Basin. Unfortunately this zone is dangerous until about level 75. Borean Tundra, Howling Fjord and Grizzly Hills contain reasonable supplies of herbs, particularly Goldclover. These zones are fairly safe at level 70. Ice-covered parts of Dragonblight and Zul'Drak contain "Frozen Herbs". Storm Peaks and Icecrown require level 77 (allowing flight) to travel across. They contain Icethorn and Lichbloom, which tend to give the greatest amount of Icy Pigment. Northrend flowers sometimes give Crystallized Life (10 make an Eternal Life, similar to Primal Life) and Frost Lotus (which cannot be milled).

Leveling 350-430

Leveling starts as normal, by making inks and then producing scrolls with those inks. Only Northrend materials are used here. If Outland herbs are plentiful (or much cheaper than Northrend herbs), make Ethereal Ink and produce glyphs between skill 355 and 360 (see Leveling 290-350).

At skill 385 you will learn Northrend Inscription Research. Like other Research, this has a 20 hour cooldown. You must discover one major glyph at skill 385, which you will then use to level to 400. If you do not make a discovery, you must wait 20 hours and try again: There is no other known way to reach skill 400!

Leveling from skill 400 to 430 simply means making scrolls.

The cost of vendor materials and trained recipes are quite high: The Resilient Parchment you need to level from 350 to 430 will cost about 75 gold in total. Each trained recipe costs at least 5 gold. And Grand Master rank itself costs 35 gold.
At skill 400 you will gain the ability to "enchant" your shoulders with Master's Inscriptions. These are the main personal benefit of Inscribing. There is a small chance of a skill-up at 400, so it is worth enchanting your shoulders as soon as possible. Master's Inscriptions appear as abilities in your Spell Book.
Leveling Inscription from Skill 350
Your SkillMakePartsInscription SkillNote
FromTo#Options#PartOrangeYellowGreenGrey
35035594Ink of the Sea188Azure Pigment (2)350350350355-
3553605Scroll of Spirit VII (2)5Ink of the Sea (1)355360365370-
10Resilient Parchment (2)
3603655Scroll of Intellect VII (2)5Ink of the Sea (1)360365370375-
10Resilient Parchment (2)
3653705Scroll of Strength VII (2)5Ink of the Sea (1)365370375380-
10Resilient Parchment (2)
3703755Scroll of Agility VII (2)5Ink of the Sea (1)370375380385-
10Resilient Parchment (2)
37537914Snowfall Ink28Icy Pigment (2)375375375380Use all the rare pigment available.
3793851111Ink of the Sea (1)375380385390-
11Resilient Parchment (1)
3853861Northrend Inscription Research3Ink of the Sea (3)385425437450-
5Resilient Parchment (5)
1Snowfall Ink (1)
38640025[Any Discovered Major Glyph]25Ink of the Sea (1)385390397405Level using the major glyph you discovered.
25Resilient Parchment (1)
4004055Scroll of Stamina VIII (2)5Ink of the Sea (1)400405410415-
10Resilient Parchment (2)
4054105Scroll of Spirit VIII (2)5Ink of the Sea (1)405410415420-
10Resilient Parchment (2)
4104155Scroll of Intellect VIII (2)5Ink of the Sea (1)410415420425-
10Resilient Parchment (2)
4154205Scroll of Strength VIII (2)5Ink of the Sea (1)415420425430-
10Resilient Parchment (2)
42043015Scroll of Agility VIII (2)15Ink of the Sea (1)420425430435-
30Resilient Parchment (2)
Keep the extra Snowfall Ink for Northrend Inscription Research. You will need to research to learn most "Northrend" glyphs.
Skilled leatherworkers can make a Pack of Endless Pockets. This 32-slot bag can be used to store Inscription materials and products: From pigments and inks, to cards and glyphs. Almost everything a Scribe needs, except herbs.

Leveling 430-450

Between skill 430 and 440, there are no good leveling options:

The best strategy is stop power-leveling Inscription at about skill 430, and simply conduct regular Northrend Inscription Research until skill 440. There are over 80 major glyphs to be discovered: It is likely you will be reach at least skill 440 by the time you have discovered them all.

If you are determined to reach 440 as fast as possible:

An alternative is the production of a glyph discovered from Book of Glyph Mastery research. Materials required vary between glyphs - most do not used Ink of the Sea.

Finally, between skill 440 and 450, make Runescroll of Fortitude. This recipe is trained from Northrend trainers. It is yellow at skill 440, but remains green from 442 to 450. Each set of scrolls only requires 1 Snowfall Ink (and 5 Resilient Parchments).

Not enough Snowfall Ink? Ink of the Sea can be traded for other inks in Dalaran. Simply visit Jessica Sellers in the Dalaran Inscription store.
El Clapping There is nothing available at Inscription skill 450 (except a Feat of Strength achievement for the first scribe on the realm to reach 450). You should consider carefully whether power-leveling to 450 now is a good use of your time.

Trained Inscriptions 350-450

Inscriptions from Skill 350
ItemInscription SkillParts
OrangeYellowGreenGrey
Ink of the Sea350350350355Azure Pigment (2)
Scroll of Recall III350350350355
350355360365
Scroll of Stamina VII (2)350355360365
Armor Vellum III (2)350355370385
Rituals of the New Moon350375387400
Twilight Tome350375387400
Scroll of Spirit VII (2)355360365370
Scroll of Intellect VII (2)360365370375
Scroll of Strength VII (2)365370375380
Scroll of Agility VII (2)370375380385
Snowfall Ink375375375380Icy Pigment (2)
375380382385
375380385390
[Any Discovered Major Glyph]385390397405
Northrend Inscription Research385425437450
Glyph of Polymorph400400400405
400400400405Snowfall Ink
Scroll of Stamina VIII (2)400405410415
Weapon Vellum III (2)400405410415
400425437450
Darkmoon Card of the North400450462475
Scroll of Spirit VIII (2)405410415420
Scroll of Intellect VIII (2)410415420425
Scroll of Strength VIII (2)415420425430
Scroll of Agility VIII (2)420425430435
Runescroll of Fortitude (5)440440442460

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